also  Kupf*fer's cell  n :  a fixed macrophage of the walls of the liver sinusoids that is stellate with a large oval nucleus and the cytoplasm commonly packed with fragments resulting from phagocytic action
 
Kupffer, Karl Wilhelm von (1829-1902), German anatomist. Kupffer described the large stellate cells in the lining of the sinusoids of the liver first in 1876 and again in 1899. His observations led to a better understanding of the reticuloendothelial system.
 
 
 
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