adj 1  :  being a complete self-contained system with nothing transferred in or out <a thermodynamic system>   2  :  covered by unbroken skin <a fracture>   3  :  not discharging pathogenic organisms to the outside <a case of tuberculosis>  - compare OPEN2   .
 
 
 
Similar sounding terms:  cal·cite  cal·los·i·ty  cal·loused  Cu·lic·i·dae 
 
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