n 1  :  interruption of normal physiological function (as transmission of nerve impulses) of a tissue or organ  2  :  the process of reducing the phagocytic capabilities of the reticuloendothelial system by loading it with harmless material (as India ink or lampblack) which engages its cells in phagocytosis and prevents them from reacting to new antigenic material - compare BLOCKING ANTIBODY 
vt, block*ad*ed  block*ad*ing  :  to subject to blockade .
 
 
 
Similar sounding terms:  black·out  black out  bow·legged 
 
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