vb, -tat*ed  -tat*ing vt  1  :  to provoke impatience, anger, or displeasure in  2  :  to cause (an organ or tissue) to be irritable  :  produce irritation in <harsh soaps may the skin>   3  :  to produce excitation in (as a nerve)  :  cause (as a muscle) to contract vi  :  to induce irritation .
 
 
 
Similar sounding terms:  ir·ra·di·ate 
 
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