also  Ma*rie-Strüm*pell's disease  n :  ANKYLOSING SPONDYLITIS
 
Marie, Pierre (1853-1940), French neurologist. Marie began his career in neurology under the tutelage of the celebrated neurologist Jean-Martin Charcot at the Salptrière clinic. Known for his astute clinical judgments, he was responsible for a number of classic descriptions. From 1886 to 1891 he produced the first description and study of acromegaly. His study of this disorder of the pituitary gland constituted a fundamental contribution to the developing science of endocrinology. In 1906 he published three papers on aphasia that generated controversy because his views on language disorders challenged the widely accepted views of Paul Broca. Marie published his description of ankylosing spondylitis in 1898.
 
Strümpell, Ernst Adolf Gustav Gottfried von (1853-1925), German neurologist. Strümpell was at various times professor of medicine at Leipzig, Breslau, and Vienna. He is credited with classic descriptions of polioencephalomyelitis in children (1885) and pseudosclerosis of the brain (1898). In 1883-1884 he published a two-volume text on the pathology and treatment of internal diseases. The second volume included his original description of ankylosing spondylitis. The disease was described independently by Pierre Marie in 1898; it is now sometimes called Marie-Strümpell disease.
 
 
 
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