n :  an increase in the symptoms of a spirochetal disease (as syphilis, Lyme disease, or relapsing fever) occurring in some persons when treatment with spirocheticidal drugs is started - called also Herxheimer reaction 
 
Jarisch, Adolf (1850-1902), Austrian dermatologist. Jarisch published his description of the Jarisch-Herxheimer reaction in 1895, seven years before Herxheimer published his own description.
 
Herxheimer, Karl (1861-1944), German dermatologist. Herxheimer published his description of the Jarisch-Herxheimer reaction in 1902. In that same year he also described acrodermatitis chronica atrophicans.
 
 
 
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