also  Creutz*feld-Ja*cob disease  n :  a rare progressive fatal encephalopathy now usu. considered to be caused by a prion and marked by the development of porous brain tissue, premature dementia in middle age, and gradual loss of muscular coordination - called also Jakob-Creutzfeldt disease 
 
Creutzfeldt, Hans Gerhard (1885-1964), and Jakob, Alfons Maria (1884-1931), German psychiatrists. Creutzfeldt published his description of the disease now known as Creutzfeldt-Jakob disease in 1920. A year later in the same neurological journal Jakob offered his description. Although Creutzfeldt's description is the original one, Jakob's is the better known of the two, so the disease is named in honor of both men.
 
 
 
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