n 1  :  a congenital form of spastic paralysis affecting all four limbs and held to be caused by impaired development of the pyramidal tracts  2  :  CEREBRAL PALSY
 
Little, William John (1810-1894), British physician. Little was the first eminent British orthopedic surgeon. In 1861 he presented the first complete description of congenital cerebral spastic paralysis, now known as Little's disease. He also established that there is a relationship between a mother's abnormal parturition and the occurrence of nervous disorders in the child.
 
 
 
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