n 1  :  the act or process of perforating : specif  :  the penetration of a body part through accident or disease <spontaneous of the sigmoid colon in the presence of diverticulosis -Jour. Amer. Med. Assoc.>   2 a  :  a rupture in a body part caused esp. by accident or disease  b  :  a natural opening in an organ or body part <small s opening at the bottom of the sulci -Ferdinand Canu & R. S. Bassler>  .
 
 
 
Similar sounding terms:  per·ver·sion 
 
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